Stem Cell Therapy for Knee Osteoarthritis in Frisco TX
Stem Cell Therapy for Knee Osteoarthritis is a cutting-edge treatment that uses the body’s own regenerative cells to reduce inflammation, repair damaged cartilage, and stimulate the healing process within the knee joint. By targeting the root cause of pain, Dr. Mahesh Mohan, MD, provides long-lasting relief, improves mobility, and helps you return to an active, pain-free lifestyle. For more information, contact us today or schedule an appointment online. We are conveniently located at 13052 Dallas Pkwy, Ste 220. Frisco, TX 75033.


Table of Contents:
Who is a good candidate for stem cell therapy for knee osteoarthritis?
How is stem cell therapy performed for knee joint treatment?
What are the potential benefits of stem cell therapy for knee osteoarthritis?
How effective is stem cell therapy compared to traditional treatments for knee osteoarthritis?
Personalized Stem Cell Therapy for Knee Osteoarthritis with Dr. Mahesh Mohan
Advanced Regenerative Treatment for Knee Osteoarthritis
A good candidate for stem cell therapy is typically someone diagnosed with mild to moderate osteoarthritis of the knee who has not experienced adequate relief from more traditional treatments such as physical therapy, weight management, anti-inflammatory medications, or corticosteroid injections.
Stem cell therapy may be especially beneficial for patients who want to delay or avoid knee replacement surgery and are in good general health. Ideal candidates are those without certain medical conditions that can impair healing, such as active infections, certain types of cancer, or severe, poorly controlled diabetes. Younger patients and those with less advanced joint degeneration often respond best, as they tend to have more healthy tissue for the stem cells to support.
It’s important to have realistic expectations about the potential benefits and limitations of stem cell therapy. While many patients have reported improvements, research on long-term results is still ongoing.
Stem cell therapy is a procedure designed to repair damaged tissues and promote long-term joint health.
Personalized Evaluation and Diagnosis
Your journey begins with a comprehensive consultation and evaluation by one of our experienced pain management physicians. Advanced imaging, such as MRI or X-rays, may be used to assess the extent of knee joint damage. This detailed assessment allows us to determine if stem cell therapy is the most appropriate solution for your specific condition.
State-of-the-Art Stem Cell Harvesting and Preparation
If you are a candidate for stem cell therapy, we use the latest techniques to harvest stem cells from your own body, typically from bone marrow or adipose (fat) tissue. These procedures are performed with your comfort in mind—bone marrow is usually aspirated from the pelvic bone under local anesthesia, while fat tissue may be collected through a gentle liposuction process. The harvested tissue is then processed in a specialized laboratory to concentrate and isolate the stem cells for maximum effectiveness.
Precise, Image-Guided Injections
Our team at Pain Specialists of Frisco utilizes advanced imaging guidance—such as ultrasound or fluoroscopy—to ensure the concentrated stem cells are accurately injected into the affected knee joint. This precision helps maximize the potential for tissue regeneration and symptom relief. The entire outpatient procedure is typically completed within a few hours, allowing you to return home the same day.
Comprehensive Aftercare and Rehabilitation
Following your stem cell injection, our team provides detailed aftercare instructions and, when appropriate, recommends physical therapy to support optimal recovery and joint function. Over the ensuing weeks and months, the stem cells work within your knee to reduce inflammation, stimulate cartilage repair, and enhance mobility. We schedule regular follow-up appointments at Pain Specialists of Frisco to monitor your progress, answer your questions, and adjust your treatment plan as needed.
One of the primary advantages of stem cell therapy is its potential to reduce pain and inflammation in the knee, leading to improved joint function and mobility. By promoting the repair and possible regeneration of damaged cartilage—a key factor in the progression of osteoarthritis—stem cell therapy may help slow the course of the disease. For many patients, this can mean delaying or even avoiding more invasive procedures like knee replacement surgery.
Stem cell therapy may also enhance your body’s natural healing processes. Stem cells secrete growth factors and other vital molecules that help reduce inflammation and support tissue repair within the knee. Many of our patients have experienced a better quality of life, increased participation in physical activities, and a decreased reliance on pain medications following stem cell treatment.
While ongoing research continues to clarify the long-term benefits and safety of stem cell therapy, early results are encouraging. At Pain Specialists of Frisco, our team stays at the forefront of these developments to provide you with the most promising options for managing knee osteoarthritis—especially if conventional treatments have not delivered the relief you need.
Knee osteoarthritis can severely impact your daily life due to pain, stiffness, and reduced mobility. Our clinic offers a comprehensive approach to managing knee osteoarthritis, including both established treatments and advanced regenerative options like stem cell therapy.
Traditional vs. Regenerative Treatments
Traditional treatments for knee osteoarthritis—such as lifestyle modifications, physical therapy, NSAIDs, corticosteroid or hyaluronic acid injections, and, in severe cases, total knee replacement—remain the cornerstone of care. These therapies primarily focus on symptom management, providing pain relief and improving function, which can be especially effective for many of our patients.
Stem cell therapy, particularly with mesenchymal stem cells (MSCs) sourced from bone marrow or adipose tissue, represents a newer, regenerative approach. Unlike traditional treatments, stem cell therapy aims to promote tissue repair and potentially regenerate damaged cartilage, addressing the underlying degeneration of the joint.
At Pain Specialists of Frisco, we closely review and follow the latest research to ensure our patients receive the most evidence-based recommendations. Current studies on stem cell therapy for knee osteoarthritis show mixed results: some patients experience improvement in pain, function, and quality of life, while others see little to no benefit. Most available research is limited in size and duration, and more high-quality studies are needed to determine the true long-term effectiveness and safety of stem cell therapy compared to traditional approaches.
At Pain Specialists of Frisco, Dr. Mahesh Mohan, MD, offers advanced stem cell therapy for knee osteoarthritis, providing a non-surgical alternative to traditional treatments. With over 25 years of experience, Dr. Mohan uses regenerative medicine techniques to promote healing and alleviate pain in affected knee joints.
Stem cell therapy aims to address the underlying causes of knee osteoarthritis by promoting cartilage repair and reducing inflammation, potentially delaying or eliminating the need for knee replacement surgery. Patients often experience improved mobility, reduced pain, and enhanced quality of life following treatment. Dr. Mohan’s personalized approach ensures that each patient receives a tailored treatment plan that aligns with their specific health needs and goals.
Our team at Pain Specialists of Frisco is committed to providing the safest and most effective treatments tailored to each patient’s needs and goals. For many, traditional therapies offer predictable relief and have a well-established safety profile. For those interested in regenerative options like stem cell therapy, we offer thorough consultations to discuss current evidence, realistic expectations, and individual suitability for treatment. For more information, contact us or book an appointment online. We are conveniently located at 13052 Dallas Pkwy, Ste 220. Frisco, TX 75033. We serve patients from Frisco TX, Little Elm TX, Prosper TX, The Colony TX, Celina TX, Addison TXand surrounding areas.


Additional Services You May Need
▸ Lumbar and Cervical Epidurals
▸ Facet Injections
▸ Trigger Point Injections
▸ Sacroiliac Injections
▸ Caudal Injections
▸ Radiofrequency Ablation
▸ Spinal Cord Stimulator Placement
▸ Chronic Pain Medication Management
▸ AVN (Avascular Necrosis of Femus)
▸ Rotator Cuff Treatment
▸ PRP Therapy
▸ Rhizotomy Neck